side effect

Formal Definition

Dose-related, therapeutically-unrelated adverse drug reaction.

Edwards I.R., Aronson J.K. (2000) Adverse drug reactions: definitions, diagnosis, and management. Lancet: 356 : 1255-9 P. 1255

A side effect, or adverse reaction, is an unintended response to a medication. Side effects are generally regarded as being harmful, and may occur after a single dose or prolonged administration.

  • Categories: Pharmacokinetics, Pharmacovigilance