limits of quantification

Formal Definition

The Lower Limit Of Quantification (LLOQ) and Upper Limit Of Quantification (ULOQ) are the lowest and highest quantity of a substance that can be quantitatively determined with a stated acceptable precision and accuracy, under stated experimental conditions.

Guidance Document on Good In Vitro Method Practices (GIVIMP)
  • Abbreviation(s): LOQ
  • Categories: Pharmacokinetics, Pharmacovigilance