cytotoxicity

Formal Definition

General cytotoxicity (or basal cytotoxicity) is the result of toxic effects on structures and functions common to all cells of the body, such as DNA, chromosomes, mitochondria, the cytoskeleton and various membranes.

Guidance Document on Good In Vitro Method Practices (GIVIMP)
  • Categories: Pharmacokinetics, Pharmacovigilance